Cardiac Assist, Inc. Greg Johnson, PhD Director of Regulatory Affairs 240 Alpha Drive Pittsburgh, PA 15238 Re: K160257 Trade/Dev
![Successful use of Protek Duo cannula to provide veno-venous extra-corporeal membrane oxygenation and right ventricular support for acute respiratory distress syndrome in an adolescent with complex congenital heart disease - Niranjan Vijayakumar, Successful use of Protek Duo cannula to provide veno-venous extra-corporeal membrane oxygenation and right ventricular support for acute respiratory distress syndrome in an adolescent with complex congenital heart disease - Niranjan Vijayakumar,](https://journals.sagepub.com/cms/10.1177/0267659120923880/asset/images/large/10.1177_0267659120923880-fig2.jpeg)
Successful use of Protek Duo cannula to provide veno-venous extra-corporeal membrane oxygenation and right ventricular support for acute respiratory distress syndrome in an adolescent with complex congenital heart disease - Niranjan Vijayakumar,
![Extracorporeal Membrane Oxygenation with Right Ventricular Assist Device for COVID-19 ARDS - ScienceDirect Extracorporeal Membrane Oxygenation with Right Ventricular Assist Device for COVID-19 ARDS - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0022480421001566-gr2.jpg)
Extracorporeal Membrane Oxygenation with Right Ventricular Assist Device for COVID-19 ARDS - ScienceDirect
![Oxygenated right ventricular assist device with a percutaneous dual-lumen cannula as a bridge to lung transplantation - Harano - Journal of Thoracic Disease Oxygenated right ventricular assist device with a percutaneous dual-lumen cannula as a bridge to lung transplantation - Harano - Journal of Thoracic Disease](https://cdn.amegroups.cn/journals/pbpc/files/journals/2/articles/61944/public/61944-PB7-4102-R1.jpg/w300)
Oxygenated right ventricular assist device with a percutaneous dual-lumen cannula as a bridge to lung transplantation - Harano - Journal of Thoracic Disease
![Protek Duo Rapid Deployment cannulation utilized to bridge to durable heartware left ventricular assist device - Ghannam - 2020 - Journal of Cardiac Surgery - Wiley Online Library Protek Duo Rapid Deployment cannulation utilized to bridge to durable heartware left ventricular assist device - Ghannam - 2020 - Journal of Cardiac Surgery - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/46310d85-32db-4517-9294-e43a4c8412f5/jocs14775-fig-0002-m.jpg)
Protek Duo Rapid Deployment cannulation utilized to bridge to durable heartware left ventricular assist device - Ghannam - 2020 - Journal of Cardiac Surgery - Wiley Online Library
![Fracture of dual lumen cannula leading to cerebrovascular accident in a patient supported with ECMO | Journal of Artificial Organs Fracture of dual lumen cannula leading to cerebrovascular accident in a patient supported with ECMO | Journal of Artificial Organs](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs10047-021-01306-z/MediaObjects/10047_2021_1306_Fig1_HTML.jpg)
Fracture of dual lumen cannula leading to cerebrovascular accident in a patient supported with ECMO | Journal of Artificial Organs
![A) Schematic illustration of the ProtekDuo ® cannula in-situ with pump... | Download Scientific Diagram A) Schematic illustration of the ProtekDuo ® cannula in-situ with pump... | Download Scientific Diagram](https://www.researchgate.net/publication/301899758/figure/fig1/AS:384446755819520@1468670657061/A-Schematic-illustration-of-the-ProtekDuo-R-cannula-in-situ-with-pump-attached-to-the.png)
A) Schematic illustration of the ProtekDuo ® cannula in-situ with pump... | Download Scientific Diagram
Perfusionist Keypage on Instagram: "Have you ever wondered if there is a way to provide VV ECLS support while supporting the right ventricle by offloading it? There are a few options, but
![Successful Use of Protek Duo Cannula to Provide Veno-Venous Extra-Corporeal Membrane Oxygenation and Right Ventricular Support for Acute Respiratory Distress Syndrome in an Adolescent with Complex Congenital Heart Disease - Perfusion.com Successful Use of Protek Duo Cannula to Provide Veno-Venous Extra-Corporeal Membrane Oxygenation and Right Ventricular Support for Acute Respiratory Distress Syndrome in an Adolescent with Complex Congenital Heart Disease - Perfusion.com](https://perfusion.com/wp-content/uploads/2019/01/right-ventricle.jpg)
Successful Use of Protek Duo Cannula to Provide Veno-Venous Extra-Corporeal Membrane Oxygenation and Right Ventricular Support for Acute Respiratory Distress Syndrome in an Adolescent with Complex Congenital Heart Disease - Perfusion.com
![Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device | Protocol Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device | Protocol](https://www.jove.com/files/ftp_upload/62951/62951fig04large.jpg)
Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device | Protocol
Right Ventricular Dysfunction or Failure with ECLS - ECMO Resource | A space for ECMO Specialists and their interdisciplinary ECMO teams to share
![Results of concomitant groin-free percutaneous temporary RVAD support using a centrifugal pump with a double-lumen jugular venous cannula in LVAD patients. | Semantic Scholar Results of concomitant groin-free percutaneous temporary RVAD support using a centrifugal pump with a double-lumen jugular venous cannula in LVAD patients. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/8fabf627cdb7145511f82e49378eddb7db39333b/3-Figure1-1.png)
Results of concomitant groin-free percutaneous temporary RVAD support using a centrifugal pump with a double-lumen jugular venous cannula in LVAD patients. | Semantic Scholar
![Adel Tash on X: "VV ECMO using a Tandem heart pump and a PROTEK Duo dual cannula an interesting technique http://t.co/VQ4g8ifZQK" / X Adel Tash on X: "VV ECMO using a Tandem heart pump and a PROTEK Duo dual cannula an interesting technique http://t.co/VQ4g8ifZQK" / X](https://pbs.twimg.com/media/CBIqqGBU0AALe3L.jpg)